Cervical Cancer

Cancer Care Alberta

The evidence-based recommendations described below outline the standard follow-up procedures for cervical cancer surveillance, and are intended to assist you in providing optimal cancer follow-up care for your patient; these recommendations are not intended to be a substitute for clinical judgement.

Surveillance Activities & Timelines

In general, follow-up is recommended every 3-6 months for the first 2-3 years, then annually. Please review the detailed progress notes for your patient’s stage and the exact schedule recommended for your patient. Follow-up activities include:

  • General assessment including complete history and physical exam, elicitation of symptoms, speculum exam, and digital pelvic +/- rectal exam.
    • Vaginal or cervical vault cytology examination is recommended annually except in patients treated with radiotherapy. Pap smears are not a substitute for a careful pelvic examination.

Patients with an abnormal cytology result should be referred for colposcopy. Please follow the TOP guideline recommendations for cervical cancer screening and referral.

Symptomatic patients should undergo appropriate tests to rule out a recurrence.


Red Flags

Please be aware of these potential symptoms of cervical cancer recurrence:

  • Change in bowel habits
  • Detection of a mass
  • Persistent pain, especially in the abdomen, pelvis, or lower back
  • Unexplained vaginal bleeding or discharge
  • Unexplained weight loss
  • Urinary symptoms

Patients who display symptoms suggestive of recurrence should undergo biopsy and/or imaging.

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Referrals for Recurrence

Patients with confirmed recurrence should be referred back to their original Cancer Centre/oncologist. Referrals can be faxed to the Gynecologic Oncology triage coordinator at: 403-521-3245 (Tom Baker Cancer Centre/Southern Alberta) or 780-432-8681 (Cross Cancer Institute/Northern Alberta). If you are unable to reach the triage coordinator, search "cancer" in the Alberta Referral Directory for the most up-to-date information and instructions for referral.

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Complications & Late Effects of Treatment

Following treatment for cervical cancer, your patient may present with some of the complications outlined below. Continue to monitor and address concerns related to cancer therapy.

 
Complication Treatment-Related Causes Actions
Bladder dysfunction
  • Chemoradiation
  • Surgery
Symptoms such as urinary incontinence, retention, frequency, urinary tract infection, and hematuria should be treated as appropriate. Referral to urology for ongoing management can be considered.
Chronic GI symptoms
  • Radiation
  • Surgery
Symptoms such as chronic diarrhea, fecal leakage, and pain should be treated as appropriate. Referral to GI for ongoing management can be considered.
Fatigue
  • Chemotherapy
  • Radiation
Fatigue should start to improve within months of treatment completion. Persistent or recurrent fatigue warrants further work-up to rule out other potential causes.
Lymphedema
  • Surgery
  • Radiation
Early symptoms include leg heaviness or discomfort and may be present with/without overt swelling. Referral to local rehabilitation services (e.g. physiotherapy) or lymphedema clinic can be made. More information can be found in the lymphedema resource.
Menopausal symptoms
  • Radiation
  • Chemotherapy
  • Surgery
  • Hormones
Some patients will experience new symptoms of menopause after treatment. During the active follow-up phase, patients manifesting symptoms of menopause such as vaginal dryness and hot flashes will be monitored as applicable by the oncology treatment team.
Deep venous thrombosis (DVT) or pulmonary embolus (PE)
  • Tamoxifen
Confirm with ultrasound of affected extremity (DVT) or CT for PE. Stop Tamoxifen and commence anticoagulation. Consult medical oncologist for direction.
Psychosocial distress
  • Stress of cancer treatment
  • Fear of recurrence
  • Post-treatment adjustments
Increasing helplessness /hopelessness, distress, anxiety or depression may be present. Patients experiencing these symptoms should be encouraged to inform their oncology treatment team for appropriate psychosocial referral. More information about fear of recurrence is found in the FCR resource.
Sexual dysfunction
  • Radiation
  • Surgery
Vaginal shortening, pain, decreased lubrication, and decreased arousal may occur. See below for more information.
 

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Specific Concerns for Cervical Cancer Patients

Sexual Dysfunction

Treatment for cervical cancer can have significant impacts on sexual function and health. The Oncology and Sexuality, Intimacy, and Survivorship (OASIS) program assists patients to manage physical and emotional concerns.

More information about sexual dysfunction and the OASIS program is found in the Cervical Cancer Transfer of Care Physician Letter.

Menopause

Some patients treated for cervical cancer may experience early menopause as a result. Patients are encouraged to report concerns regarding managing menopausal symptoms with their treatment team.

HPV Vaccine

Patients who have had cervical cancer do not need to get the HPV vaccine. For more information, please visit screeningforlife.ca.

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Note: The information on this page was adapted from the AHS Guideline Resource Unit's Cancer of the Uterine Cervix guideline, and the accompanying Cervical Cancer Transfer of Care Physician Letter. Also available is the Cervical Cancer Transfer of Care Patient Letter.